Tohoku University Technology: Treatment and Prevention Agents for Chronic Kidney Disease Complications: T22-116
Components found in mammalian milk suppress the progression of kidney disorders, sarcopenia, and anemia.
Chronic kidney disease currently affects about 1 in 8 adults and is said to be a new national disease in Japan. The treatment aims to slow the progression of symptoms, particularly to prevent the progression to end-stage renal failure and the onset of cardiovascular diseases. CKD also has complications such as bone disorders, muscle atrophy (sarcopenia), and anemia, and there are no effective treatments available. This invention relates to the effects of a protein called lactoferrin (Lf) on the progression and complications of chronic kidney disease (CKD). It was found that the administration of Lf has both preventive effects before the onset of CKD and therapeutic effects after its onset in adenine-induced renal failure model mice (Reference 1). Specifically, the effects of Lf in suppressing sarcopenia (reduction of muscle cross-sectional area, decrease in the accumulation of uremic toxins in muscles), anemia, renal atrophy, tubular interstitial damage, decline in kidney function, and inflammation and fibrosis in the kidneys were confirmed.
- Company：Tohoku Techno Arch Co., Ltd.
- Price：Other
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